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PDK-IN-1

PDK-IN-1 (compound 7o) is a dual inhibitor of pyruvate dehydrogenase kinase (PDK1) and HSP90 with IC50 values of 0.03 μM and 0.1 μM, respectively. It targets the PDH/PDK axis and has demonstrated significant antitumor efficacy by reducing tumor mass in in vivo studies.

Product Specifications

CAS Number

2897696-10-3

Field of Research

Metabolism Research, Signal Transduction

Smiles

CN1C=C (C=2C1=NC=C (Br) C2) C=3C (=NN=C (N) N3) C=4C=5C (NC4) =CC=C (OC) C5

Molecular Formula

C20H16BrN7O

Molecular Weight

450.29

Storage Conditions

-20°C

Notes

For research use only.

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