PROTAC pan-IAP degrader-1

Compound 9 is a potent pan-IAP degrader PROTAC that induces the degradation of XIAP, cIAP1, and cIAP2 with low nanomolar DC50 values in MM.1S cells. This tool compound is used in cancer research, particularly for studying apoptosis and IAP protein function in both cellular and biochemical assays.