PROTAC CDK9 degrader-5
PROTAC CDK9 degrader-5 is a selective proteolysis-targeting chimera that induces proteasomal degradation of CDK9 isoforms 42 and 55, with DC50 values of 0.10 μM and 0.14 μM, respectively. This compound is a valuable chemical tool for investigating CDK9 biology in cancer research and has demonstrated utility in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
2935587-89-4
Field of Research
Cell Biology, Epigenetics & Chromatin, Pharmacology & Drug Discovery
Smiles
O=C1C=2C (C (=O) N1C3C (=O) NC (=O) CC3) =CC=CC2OCC (NCCCCCCCCCCC (=O) N4CCC (NC (=O) C=5C (NC (=O) C6=C (Cl) C=CC=C6Cl) =CNN5) CC4) =O
Molecular Formula
C42H48Cl2N8O9
Molecular Weight
879.78
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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