Cys-McMMAF

Cys-McMMAF is the active metabolite released from the antibody-drug conjugate AlMcMMAF. It exhibits potent antitumor activity by disrupting microtubule dynamics, as demonstrated in vivo using H1975 and MDA-MB-361-DYT2 mouse xenograft models. This compound is a valuable tool for researching ADC payload mechanisms and cancer therapeutics.

Product Specifications

CAS Number

1160590-05-5

Field of Research

Signal Transduction

Smiles

[H][C@]1 (CCCN1C (=O) C[C@@H] (OC) [C@H] ([C@@H] (C) CC) N (C) C (=O) [C@@H] (NC (=O) [C@H] (C (C) C) N (C) C (=O) CCCCCN1C (=O) CC (SC[C@H] (N) C (O) =O) C1=O) C (C) C) [C@H] (OC) [C@@H] (C) C (=O) N[C@@H] (Cc1ccccc1) C (O) =O