SIRT1/2/3-IN-1
SIRT1/2/3-IN-1 is a potent, selective, and cell-permeable pan-sirtuin inhibitor with IC50 values of 0.54 μM (SIRT1), 0.253 μM (SIRT2), and 0.72 μM (SIRT3) . It is a valuable chemical probe for investigating sirtuin biology in cancer research, applicable in both cellular and biochemical assays.
Product Specifications
CAS Number
2413212-06-1
Field of Research
Cell Biology, Epigenetics & Chromatin, Molecular Biology
Smiles
C (N[C@H] (C (N[C@H]1CC=2C=CC (=CC2) OCCCCCNC (=O) [C@H] (CCSC) NC1=O) =O) CCCCNC (C) =S) (=O) [C@@H]3CC=4C=CC (=CC4) OCCCC (=O) N[C@@H] (CC5=CN=CN5) C (=O) N3
Molecular Formula
C46H63N9O8S2
Molecular Weight
934.18
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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