MS15

MS15 is a potent and selective AKT-targeting PROTAC degrader, demonstrating nanomolar IC50 values against AKT1 (798 nM), AKT2 (90 nM), and AKT3 (544 nM) . This molecule is a valuable chemical tool for studying AKT signaling in cancer research and has been utilized in both cellular and in vivo models to investigate oncogenic pathways and therapeutic potential.