PROTAC HDAC6 degrader 1
Compound A6 is a potent and selective PROTAC that degrades HDAC6 with a DC50 of 3.5 nM. This molecule induces apoptosis and shows notable antiproliferative activity in myeloid leukemia cell lines in vitro, supporting its investigation in oncology and hematology research.
Product Specifications
CAS Number
2785404-76-2
Field of Research
Cell Biology, Epigenetics & Chromatin, Molecular Biology, Pharmacology & Drug Discovery
Smiles
O=C1C=2C (C (=O) N1C3C (=O) NC (=O) CC3) =CC=CC2OCC (NCCCCCCCC (NC4=CC=C (C (NCCCCCCC (NO) =O) =O) C=C4) =O) =O
Molecular Formula
C37H46N6O10
Molecular Weight
734.8
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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