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Nampt degrader-2

Nampt degrader-2 is a fluorescent PROTAC molecule that induces degradation of NAMPT via the VHL E3 ligase, with an IC50 of 41.9 nM. This degradation depletes cellular NAD+ and demonstrates potent antitumor activity in research models, supporting its use in oncology and metabolic studies.

Product Specifications

Field of Research

Metabolism Research, Pharmacology & Drug Discovery

Molecular Formula

C59H73N9O7S

Molecular Weight

1052.33

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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