STING agonist-25
STING agonist-23 (CF505) is a synthetic small molecule that potently activates the STING pathway, leading to TBK1/IRF3 phosphorylation and robust induction of type I interferons and pro-inflammatory cytokines. Its activity, demonstrated in cellular studies, supports its use in immuno-oncology and antiviral research, including against coronaviruses.
Product Specifications
CAS Number
2408723-10-2
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery; Cell Biology
Smiles
C (/C=C/CN1C=2C (N=C1NC (=O) C=3N (CC) N=C (C) C3) =CC (C (N) =O) =CN2) N4C=5C (N=C4NC (=O) C=6N (CC) N=C (C) C6) =CC (C (N) =O) =CC5OCCCO
Molecular Formula
C36H41N13O6
Molecular Weight
751.79
Storage Conditions
-20°C
Notes
For research use only.
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