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STING agonist-25

STING agonist-23 (CF505) is a synthetic small molecule that potently activates the STING pathway, leading to TBK1/IRF3 phosphorylation and robust induction of type I interferons and pro-inflammatory cytokines. Its activity, demonstrated in cellular studies, supports its use in immuno-oncology and antiviral research, including against coronaviruses.

Product Specifications

CAS Number

2408723-10-2

Field of Research

Immunology & Inflammation, Pharmacology & Drug Discovery; Cell Biology

Smiles

C (/C=C/CN1C=2C (N=C1NC (=O) C=3N (CC) N=C (C) C3) =CC (C (N) =O) =CN2) N4C=5C (N=C4NC (=O) C=6N (CC) N=C (C) C6) =CC (C (N) =O) =CC5OCCCO

Molecular Formula

C36H41N13O6

Molecular Weight

751.79

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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