PROTAC STAT3 degrader-2
PROTAC STAT3 degrader-2 is a selective small molecule that degrades STAT3 protein, demonstrating a DC50 of 3.54 μM in Molm-16 cells. This compound serves as a valuable chemical tool for investigating STAT3-dependent oncogenic signaling in cancer research, including both in vitro and in vivo experimental models.
Product Specifications
CAS Number
2429877-78-9
Field of Research
Cancer Biology, Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology
Smiles
O=C1C=2C (C (=O) N1C3C (=O) NC (=O) CC3) =CC=CC2C#CCCCCCC (=O) N4C[C@H] (NC (=O) C5=CC=6C (N5) =CC=C (C (P (=O) (O) O) (F) F) C6) C (=O) N7[C@@] (CC4) (CC[C@H]7C (N[C@H] (C (NC (C8=CC=CC=C8) C9=CC=CC=C9) =O) CCC (N) =O) =O) [H]
Molecular Formula
C59H60F2N9O13P
Molecular Weight
1172.13
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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