Luxdegalutamide
Luxdegalutamide (ARV-766) is an oral PROTAC degrader targeting the androgen receptor (AR) . It effectively degrades wild-type AR and clinically resistant mutants like L702H, H875Y, and T878A. This molecule is a valuable research tool for investigating prostate cancer mechanisms and treatment resistance in both cellular and animal models.
Product Specifications
CAS Number
2750830-09-0
Product Name Alternative
ARV 766, ARV766, ARV-766, Androgen Receptor, AndrogenReceptor, Luxdegalutamide, PROTAC
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Purity
99.95% (May vary between batches)
Solubility
DMSO:250 mg/mL (309.43 mM)
Smiles
O ([C@H]1C (C) (C) [C@H] (NC (=O) C2=CC=C (C=C2) N3CCC (CN4CCN (CC4) C5=CC (F) =C (C (N[C@@H]6C (=O) NC (=O) CC6) =O) C=C5) CC3) C1 (C) C) C7=CC (OC) =C (C#N) C=C7
Molecular Formula
C45H54FN7O6
Molecular Weight
807.95
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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