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Luxdegalutamide

Luxdegalutamide (ARV-766) is an oral PROTAC degrader targeting the androgen receptor (AR) . It effectively degrades wild-type AR and clinically resistant mutants like L702H, H875Y, and T878A. This molecule is a valuable research tool for investigating prostate cancer mechanisms and treatment resistance in both cellular and animal models.

Product Specifications

CAS Number

2750830-09-0

Product Name Alternative

ARV 766, ARV766, ARV-766, Androgen Receptor, AndrogenReceptor, Luxdegalutamide, PROTAC

Field of Research

Metabolism Research, Pharmacology & Drug Discovery

Purity

99.95% (May vary between batches)

Solubility

DMSO:250 mg/mL (309.43 mM)

Smiles

O ([C@H]1C (C) (C) [C@H] (NC (=O) C2=CC=C (C=C2) N3CCC (CN4CCN (CC4) C5=CC (F) =C (C (N[C@@H]6C (=O) NC (=O) CC6) =O) C=C5) CC3) C1 (C) C) C7=CC (OC) =C (C#N) C=C7

Molecular Formula

C45H54FN7O6

Molecular Weight

807.95

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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