CPD-1224
CPD-1224 is an orally bioavailable cereblon-binding derivative designed to selectively degrade oncogenic EML4-ALK fusions and resistant mutants like L1196M/G1202R. This PROTAC-based molecule enables targeted protein degradation research, supporting in vitro and in vivo studies on ALK-driven cancers, including non-small cell lung carcinoma.
Product Specifications
CAS Number
2891620-68-9
Field of Research
Cardiovascular Research, Neuroscience, Signal Transduction
Smiles
O=C1C2=CC=C (C=C2C (=O) N1C3C (=O) NC (=O) CC3) N4CC (C4) CN5CCC (C6=CC (OC) =C (C=C6C) NC7=NC=C (Cl) C (=N7) NC=8C=CC=CC8S (=O) (=O) C (C) C) CC5
Molecular Formula
C43H47ClN8O7S
Molecular Weight
855.4
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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