HER2-IN-13
HER2-IN-13 (Compound 33) is a potent, dual-activity small molecule inhibitor, demonstrating high potency against HER2 (IC50 = 8 nM) and activity against wild-type EGFR (IC50 = 0.40 μM) . This profile supports its application in biochemical and cellular research for investigating HER2-driven and EGFR-related oncology pathways in vitro.
Product Specifications
CAS Number
2414056-34-9
Field of Research
Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction
Smiles
O (C=1C=2C (NC3=CC (Cl) =C (OC4=CC=5N (C=N4) N=CN5) C=C3) =NC=NC2C=CC1OC) [C@H]6C (F) (F) CN (C) CC6
Molecular Formula
C26H23ClF2N8O3
Molecular Weight
568.96
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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