2'-O-Me-5-I-U-3'-phosphoramidite

This purine nucleoside analog, 2’-O-Me-5-I-U-3’-phosphoramidite, demonstrates broad antitumor activity, particularly against indolent lymphoid cancers. Its mechanisms, including DNA synthesis inhibition and apoptosis induction, have been studied in both in vitro cellular assays and in vivo preclinical models for oncology research.