SB-435495
SB-435495 is a potent and selective oral inhibitor of Lp-PLA2, exhibiting an IC50 of 0.06 nM. It serves as a key research tool for investigating the role of Lp-PLA2 in inflammatory diseases, including atherosclerosis and autoimmune uveitis, in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
304694-39-1
Product Name Alternative
Lp-PLA2, SB435495, SB 435495
Field of Research
Metabolism Research
Purity
≥98% (May vary between batches)
Solubility
DMSO:80 mg/mL (110.98 mM)
Smiles
O=C1N=C (SCC2=CC=C (F) C=C2) N (C=C1CC=3C=NN (C3) C) CC (=O) N (CC4=CC=C (C=C4) C=5C=CC (=CC5) C (F) (F) F) CCN (CC) CC
Molecular Formula
C38H40F4N6O2S
Molecular Weight
720.82
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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