SB-435495 hydrochloride
SB-435495 hydrochloride is a highly potent, selective, and orally bioavailable reversible inhibitor of Lp-PLA2, demonstrating an IC50 of 0.06 nM. This compound is a valuable research tool for investigating the role of Lp-PLA2 in atherosclerosis and inflammation in both cellular and animal models.
Product Specifications
CAS Number
304694-41-5
Field of Research
Metabolism Research
Smiles
C (C (N (CC1=CC=C (C=C1) C2=CC=C (C (F) (F) F) C=C2) CCN (CC) CC) =O) N3C (SCC4=CC=C (F) C=C4) =NC (=O) C (CC=5C=NN (C) C5) =C3.Cl
Molecular Formula
C38H41ClF4N6O2S
Molecular Weight
757.28
Storage Conditions
-20°C
Notes
For research use only.
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