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SB-435495 hydrochloride

SB-435495 hydrochloride is a highly potent, selective, and orally bioavailable reversible inhibitor of Lp-PLA2, demonstrating an IC50 of 0.06 nM. This compound is a valuable research tool for investigating the role of Lp-PLA2 in atherosclerosis and inflammation in both cellular and animal models.

Product Specifications

CAS Number

304694-41-5

Field of Research

Metabolism Research

Smiles

C (C (N (CC1=CC=C (C=C1) C2=CC=C (C (F) (F) F) C=C2) CCN (CC) CC) =O) N3C (SCC4=CC=C (F) C=C4) =NC (=O) C (CC=5C=NN (C) C5) =C3.Cl

Molecular Formula

C38H41ClF4N6O2S

Molecular Weight

757.28

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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