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SB-435495 ditartrate

SB-435495 ditartrate is a highly potent, selective, and orally bioavailable reversible inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2), with an IC50 of 0.06 nM. This compound is a valuable research tool for investigating the role of Lp-PLA2 in cardiovascular and inflammatory diseases in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

304694-43-7

Field of Research

Metabolism Research

Smiles

OC ([C@H] (O) [C@@H] (O) C (O) =O) =O.FC (F) (F) C (C=C1) =CC=C1C (C=C2) =CC=C2CN (CCN (CC) CC) C (CN3C (SCC4=CC=C (C=C4) F) =NC (C (CC5=CN (C) N=C5) =C3) =O) =O.OC ([C@H] (O) [C@@H] (O) C (O) =O) =O

Molecular Formula

C46H52F4N6O14S

Molecular Weight

1020.99

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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