MM-401 TFA
MM-401 (TFA) is a potent and selective inhibitor of the MLL1 methyltransferase, disrupting the MLL1-WDR5 interaction with an IC50 of 0.32 μM. This small molecule induces cell cycle arrest, apoptosis, and differentiation in vitro, making it a valuable chemical probe for studying MLL-rearranged leukemias.
Product Specifications
CAS Number
1442106-11-7
Field of Research
Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation
Smiles
C (C (O) =O) (F) (F) F.O=C1[C@H] (NC (=O) [C@H] (CC) NC (=O) [C@H] (CCCNC (=N) N) NC (=O) [C@@] (NC (C (C) C) =O) (C) CCCCN1) C2=CC=CC=C2
Molecular Formula
C31H47F3N8O7
Molecular Weight
700.75
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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