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84-B10

84-B10 is a protective agent against cisplatin-induced nephrotoxicity. It mitigates kidney damage by counteracting ferroptosis, reducing lipid peroxidation and mitochondrial ROS, while restoring antioxidant defenses. This small molecule is utilized in research models, both in vitro and in vivo, to study acute kidney injury and ferroptotic cell death pathways.

Product Specifications

CAS Number

698346-43-9

Field of Research

Cell Biology

Purity

99.76% (May vary between batches)

Solubility

DMSO:80 mg/mL (168.98 mM) ; H2O:< 0.1 mg/mL (insoluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.22 mM)

Smiles

O=C (O) CC (C=1C=CC=CC1) CC (=O) NC2=CC (=CC=C2OC3=CC=C (OC) C=C3) C (F) (F) F

Molecular Formula

C25H22F3NO5

Molecular Weight

473.44

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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