(±) -Evodiamine
(±) -Evodiamine is a natural topoisomerase I inhibitor that suppresses adipogenesis and inflammation via modulation of IGF-1/HIF-1α, IL-6/STAT, and NF-κB pathways. It has been studied in vitro and in vivo for its roles in inhibiting cancer cell invasion, promoting apoptosis, and blocking TNF-induced Akt activation.
Product Specifications
CAS Number
518-18-3
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Molecular Biology, Signal Transduction, Stem Cell & Developmental Biology
Purity
99.90% (May vary between batches)
Solubility
DMSO:8 mg/mL (26.37 mM) ;10% DMSO+90% Corn Oil:0.5 mg/mL (1.65 mM)
Smiles
CN1C2C3=C (C=4C (N3) =CC=CC4) CCN2C (=O) C=5C1=CC=CC5
Molecular Formula
C19H17N3O
Molecular Weight
303.36
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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