RKH
PKH is a TLR4 antagonist. PKH is a novel tripeptide and can be isolated from Akkermansia muciniphila. RKH reduces sepsis-induced inflammatory cell activation and proinflammatory factor overproduction[1].
Product Specifications
UNSPSC
12352209
Target
Toll-like Receptor (TLR)
Type
Peptides
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/rkh.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@@H](CCCCN)C(N[C@@H](CC1=CNC=N1)C(O)=O)=O)[C@H](CCCNC(N)=N)N
Molecular Formula
C18H33N9O4
Molecular Weight
439.51
References & Citations
[1]Xie S, et al. Novel tripeptide RKH derived from Akkermansia muciniphila protects against lethal sepsis. Gut. 2023 Dec 7;73 (1) :78-91.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Curated Selection
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