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BRD7-IN-1 free base

VZ185 is a PROTAC molecule that potently degrades BRD7 and BRD9 (DC50 = 4.5 and 1.8 nM, respectively) . It is constructed from a BRD7/9 inhibitor derivative linked to a VHL ligand. This compound is a valuable chemical probe for studying bromodomain function in cancer and epigenetic research, both in vitro and in vivo.

Product Specifications

CAS Number

2305379-66-0

Field of Research

Epigenetics & Chromatin, Pharmacology & Drug Discovery

Smiles

O=C1C=2C=NC=CC2C (=CN1C) C=3C=C (OC) C (=C (OC) C3) CN4CCNCC4

Molecular Formula

C22H26N4O3

Molecular Weight

394.47

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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