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Lenalidomide-PEG3-iodine

Lenalidomide-PEG3-iodine is a cereblon E3 ligase recruiting ligand connected via a PEG3 linker, used to synthesize PROTAC degraders. It is a key component in potent research degraders like SJF620 (DC50 = 7.9 nM against BTK), enabling targeted protein degradation studies in both cellular and biochemical assays.

Product Specifications

Field of Research

Pharmacology & Drug Discovery, Pharmacology & Drug Discovery; Cell Biology

Smiles

O=C (N1) C (CCC1=O) N (C2=O) CC3=C2C=CC (OCCOCCOCCI) =C3

Molecular Formula

C19H23IN2O6

Molecular Weight

502.3

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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