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(S, R, S) -AHPC-O-Ph-PEG1-NH2

(S, R, S) -AHPC-O-Ph-PEG1-NH2 (VH032-O-Ph-PEG1-NH2) is a VHL-based E3 ligase ligand-linker conjugate used to construct PROTAC molecules. It serves as a key component in PROTAC EED degrader-1, a potent degrader (pKD 9.02) of the EED protein for targeted protein degradation research in biochemical and cellular studies.

Product Specifications

CAS Number

2361117-24-8

Field of Research

Cell Biology, Pharmacology & Drug Discovery

Smiles

Cc1ncsc1-c1ccc (CNC (=O) [C@@H]2C[C@@H] (O) CN2C (=O) [C@@H] (NC (=O) COc2ccc (OCCN) cc2) C (C) (C) C) cc1

Molecular Formula

C32H41N5O6S

Molecular Weight

623.76

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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