SNIPER (ER) -110
SNIPER (ER) -51 is a heterobifunctional degrader that targets the estrogen receptor (ER) for proteasomal degradation via cIAP1 recruitment. It demonstrates potent degradation with DC50 values below 10 nM in cellular assays. This compound is a valuable chemical tool for investigating targeted protein degradation in breast cancer and ER-related disease models.
Product Specifications
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Smiles
O=C ([C@H]1N (C ([C@H] (C2CCCCC2) NC ([C@@H] (NC) C) =O) =O) C[C@@H] (OC3=CC=CC (OCCOCCOCCOCC (N (C) CCOC4=CC=C (/C (C5=CC=C (O) C=C5) =C (C6=CC=CC=C6) /CC) C=C4) =O) =C3) C1) N[C@@H]7CCCC8=C7C=CC=C8
Molecular Formula
C66H83N5O11
Molecular Weight
1122.39
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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