5-Monobutyl methotrexate
5-Monobutyl methotrexate is a research-grade small molecule functioning as an antimetabolite and immunosuppressant. It acts by inhibiting tetrahydrofolate dehydrogenase, thereby blocking tetrahydrofolate-dependent DNA synthesis. This compound is utilized in biochemical and cancer research, including in vitro studies of antifolate mechanisms.
Product Specifications
CAS Number
66147-31-7
Field of Research
Pharmacology & Drug Discovery
Smiles
NC=1C2=C (N=CC (CN (C) C3=CC=C (C (N[C@@H] (CCC (OCCCC) =O) C (O) =O) =O) C=C3) =N2) N=C (N) N1
Molecular Formula
C24H30N8O5
Molecular Weight
510.55
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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