Branaplam mesylate (1562338-42-4 free base)
Selected Variant
GTR19224399-01
Size: 100 mg
Branaplam is an orally bioavailable small molecule that potently and selectively modulates SMN2 pre-mRNA splicing to enhance production of full-length, functional SMN protein. It has demonstrated efficacy in increasing SMN protein levels in both cellular models and in vivo studies of spinal muscular atrophy, supporting its application in preclinical research for this genetic disorder.
Product Specifications
Smiles
O=C1C=C (C2=CNN=C2) C=C/C1=C3C=CC (OC4CC (C) (C) NC (C) (C) C4) =NN\3.OS (=O) (C) =O
Molecular Formula
C23H31N5O5S
Molecular Weight
489.59
Storage Conditions
-20°C
Notes
For research use only.
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