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Apoptolidin

Apoptolidin is a natural product from Nocardiopsis bacteria that selectively induces apoptosis in transformed glial cells by potently inhibiting mitochondrial F1FO-ATPase (Ki ~4-5 μM) . It serves as a valuable research tool for studying cancer cell metabolism and has demonstrated antibiotic and antifungal properties in vitro.

Product Specifications

CAS Number

194874-06-1

Field of Research

Cell Biology

Purity

>98%

Bioactivity

Apoptosis inducer

Form

Lyophilized

Solubility

Soluble in DMSO, DMF, Ethanol or Methanol

Smiles

[H][C@]1 (C[C@H] (OC) [C@@H] (O) CC\C=C (/C) \C=C/[C@@H] (O[C@@H]2O[C@@H] (C) [C@H] (OC) [C@@H] (O) [C@@H]2O) [C@H] (C) \C=C (/C) \C=C (\C) /C=C (C) /C (=O) O1) [C@@H] (O) [C@]1 (O) O[C@H] (C[C@H] (COC) O[C@H]2C[C@] (C) (O) [C@@H] (O[C@H]3C[C@@H] (OC) [C@H] (O) [C@@H] (C) O3) [C@H] (C) O2) [C@H] (C) [C@H] (O) [C@H]1C |c:10,13,31,37, t:34|

Molecular Formula

C58H96O21

Molecular Weight

1129.37

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

Fermentation product from Amycolatopsis sp.

Available Sizes

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