Cyclic ADP-ribose ammonium

Cyclic ADP-ribose ammonium salt (cADPR) is a potent second messenger derived from NAD+ that mobilizes intracellular calcium. It primarily acts by triggering calcium release from endoplasmic reticulum stores via ryanodine receptors and promoting extracellular calcium influx through TRPM2 channel activation, making it a key tool for studying calcium signaling in cellular and physiological research.