PROTAC IRAK4 degrader-6
PROTAC IRAK4 degrader-6 is a Cereblon-directed molecular glue that potently induces the degradation of interleukin-1 receptor-associated kinase 4. This tool compound enables the study of IRAK4's role in inflammation and oncology, supporting both in vitro mechanistic studies and in vivo proof-of-concept research.
Product Specifications
CAS Number
2360530-72-7
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery, Signal Transduction
Smiles
NC (=O) c1nn (cc1NC (=O) c1coc (n1) -c1ccnc (NCC (F) (F) F) c1) -c1ccc (cc1) C (=O) NCCCCCNCCNc1cccc2C (=O) N (C3CCC (=O) NC3=O) C (=O) c12
Molecular Formula
C42H41F3N12O8
Molecular Weight
898.861
Storage Conditions
-20°C
Notes
For research use only.
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