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GS-443902

GS-443902, the active triphosphate metabolite of Remdesivir, is a potent viral RNA-dependent RNA polymerase (RdRp) inhibitor. It demonstrates in vitro activity against viruses like RSV and HCV with IC50 values of 1.1 μM and 5 μM, respectively, supporting antiviral research in biochemical and cell-based assays.

Product Specifications

CAS Number

1355149-45-9

Field of Research

Cell Biology, Infectious Disease & Virology, Metabolism Research, Molecular Biology, Protein Biochemistry

Smiles

Nc1ncnn2c (ccc12) [C@@]1 (O[C@H] (COP (O) (=O) OP (O) (=O) OP (O) (O) =O) [C@@H] (O) [C@H]1O) C#N

Molecular Formula

C12H16N5O13P3

Molecular Weight

531.2

Storage Conditions

-20°C

Notes

For research use only.

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