Indole-4-carboxaldehyde
Indole-4-carboxaldehyde (ST-I4C) is a natural small molecule that mitigates methylglyoxal (MGO) -induced inflammatory responses in HepG2 cells. It functions by suppressing advanced glycation end-products (AGEs) and the expression of TNF-α and IFN-γ, while modulating the NF-κB pathway and glyoxalase-1. This compound is a useful research tool for studying oxidative stress, inflammation, and metabolic disorders in cellular models.
Product Specifications
CAS Number
1074-86-8
Product Name Alternative
ST I4C, ST-I4C, Indole4carboxaldehyde, Indole-4-carboxaldehyde, Indole 4 carboxaldehyde
Field of Research
Cell Biology, Immunology & Inflammation, Neuroscience, Signal Transduction
Purity
98.89% (May vary between batches)
Solubility
DMSO:40 mg/mL (275.56 mM)
Smiles
O=CC1=C2C=CNC2=CC=C1
Molecular Formula
C9H7NO
Molecular Weight
145.158
Storage Conditions
Store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
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