FAP-PI3KI1
FAP-PI3KI1 is a fibroblast-activated protein (FAP) -directed small molecule that selectively inhibits PI3K in FAP-expressing cells, such as those in idiopathic pulmonary fibrosis (IPF) . It demonstrates efficacy in reducing collagen production and deposition in relevant in vitro and in vivo fibrotic disease models.
Product Specifications
CAS Number
2415941-98-7
Field of Research
Cell Biology, Signal Transduction
Smiles
COc1ncc (cc1NS (=O) (=O) c1ccc (F) cc1F) -c1ccc2nccc (-c3ccc (COC (=O) OCCSSC[C@H] (NC (=O) CCC (=O) NCc4cc (ccn4) C (=O) N[C@@H] (C) C (=O) N4CC (F) (F) C[C@H]4C#N) C (O) =O) nc3) c2c1
Molecular Formula
C52H48F4N10O12S3
Molecular Weight
1177.19
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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