THK01
THK01 is a potent and selective ROCK2 inhibitor (IC50 = 5.7 nM vs. ROCK2; 923 nM vs. ROCK1) . It blocks the ROCK2-STAT3 signaling pathway, effectively inhibiting breast cancer metastasis in research models, making it a valuable tool for studying cancer biology and metastasis in vitro and in vivo.
Product Specifications
CAS Number
2226941-26-8
Field of Research
Cell Biology, Signal Transduction, Stem Cell & Developmental Biology
Smiles
O=C1C2=C3C (=C4C (=C2CN1) C=5C (N4) =CC=CC5) NC=6C3=CC (O) =CC6
Molecular Formula
C20H13N3O2
Molecular Weight
327.34
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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