Dacomitinib metabolite M2
Dacomitinib metabolite M2, also identified as the dacomitinib cysteine conjugate, is a potent inhibitor of both wild-type EGFR and the T790M mutant. This small molecule is used in biochemical and cellular research to study EGFR-driven signaling pathways and resistance mechanisms in vitro.
Product Specifications
CAS Number
1262034-38-7
Field of Research
Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction
Smiles
N (C=1C2=C (C=C (OC) C (NC (CC (CN3CCCCC3) SC[C@@H] (C (O) =O) N) =O) =C2) N=CN1) C4=CC (Cl) =C (F) C=C4
Molecular Formula
C27H32ClFN6O4S
Molecular Weight
591.1
Storage Conditions
-20°C
Notes
For research use only.
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