Acivicin hydrochloride
Acivicin hydrochloride is the hydrochloride salt of the natural glutamine analog Acivicin. It acts as a potent inhibitor of γ-glutamyltransferase (GGT) and L-asparagine synthetase, blocking nucleotide biosynthesis. This cytotoxic mechanism has been investigated in vitro and in vivo for cancer research, particularly in studies targeting glutamine-dependent metabolic pathways.
Product Specifications
CAS Number
161922-40-3
Product Name Alternative
AT125 hydrochloride, AT-125 hydrochloride, U42126 hydrochloride, U-42126 hydrochloride
Field of Research
Infectious Disease & Virology, Metabolism Research
Purity
99.12% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (15.35 mM) ; DMSO:80 mg/mL (372.02 mM)
Smiles
[C@H] (C (O) =O) (N) [C@]1 (ON=C (Cl) C1) [H].Cl
Molecular Formula
C5H8Cl2N2O3
Molecular Weight
215.04
Storage Conditions
-20°C
Notes
For research use only.
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