Prostaglandin E2 Inhibitor 3
This small molecule is a selective mPGES-1 inhibitor (IC50 = 0.2 μM) that reduces PGE2, IL-6, and 5-LO products in cellular assays and shows in vivo efficacy by inhibiting leukocyte infiltration in a murine peritonitis model at 10 mg/kg, supporting research on inflammation and related pathways.
Product Specifications
Field of Research
Pharmacology & Drug Discovery
Smiles
O=C (C1=CC=CC=C1Br) NC2=NN=C (C3=CC=C (C4=CC (O) =CC=C4) C=C3) S2
Molecular Formula
C21H14BrN3O2S
Molecular Weight
452.32
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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