GPX4 24
GPX4 24 is a potent, covalent GPX4 inhibitor derived from (1S,3R) -RSL3. It induces ferroptosis in vitro (EC50 = 0.16 μM in HT-1080 cells) and elevates lipid peroxidation markers like MDA in vivo, making it a valuable tool for studying ferroptosis in cancer research.
Product Specifications
Smiles
ClCC (N1[C@H] (CC (C2=CC=CC=C2N3) =C3[C@@H]1C4=CC=C (C=C4) S (C) (=O) =O) C (OC) =O) =O
Molecular Formula
C22H21ClN2O5S
Molecular Weight
460.93
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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