AP-1
AP-1 is a miniaturized PROTAC degrader targeting ALK fusion proteins. It potently and selectively degrades oncogenic ALK variants in vitro and reduces tumor growth in mouse xenograft models, demonstrating utility for targeted protein degradation research in oncology.
Product Specifications
Smiles
O=C (CNC1=C (C (N (C2C (NC (CC2) =O) =O) C3=O) =O) C3=CC=C1) N4CCN (C5=CC (OC) =C (NC6=NC (NC7=CC=CC=C7S (C (C) C) (=O) =O) =C (Cl) C=N6) C=C5) CC4
Molecular Formula
C39H40ClN9O8S
Molecular Weight
830.31
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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