Plipastatin A1
Plipastatin A1 is a Bacillus cereus-derived lipopeptide that potently inhibits phospholipases A2, C, and D (IC50s: 2.9, 1.3, 1.4 μM) . It suppresses LPS- and concanavalin A-induced lymphocyte blastogenesis in vitro and demonstrates in vivo immunosuppressant activity by inhibiting delayed-type hypersensitivity in mice.
Product Specifications
CAS Number
103651-09-8
Field of Research
Metabolism Research
Smiles
O=C ([C@H] (NC ([C@@H] (NC (C[C@@H] (CCCCCCCCCCCCC) O) =O) CCC (O) =O) =O) CCCN) N[C@@H] (CC1=CC=C (OC ([C@@] ([C@@H] (C) CC) ([H]) NC ([C@@H] (CC2=CC=C (O) C=C2) NC3=O) =O) =O) C=C1) C (N[C@@] ([C@H] (O) C) ([H]) C (N[C@@H] (CCC (O) =O) C (N[C@H] (C) C (N4[C@@] (C (N[C@H]3CCC (N) =O) =O) ([H]) CCC4) =O) =O) =O) =O
Molecular Formula
C72H110N12O20
Molecular Weight
1463.71
Storage Conditions
-20°C
Notes
For research use only.
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