UNC8153 TFA
UNC8153 TFA is a potent and selective degrader of the NSD2 protein, demonstrating anti-proliferative activity in MM.1S multiple myeloma cells. This compound serves as a valuable chemical probe for oncology research, particularly in studying epigenetic targets and protein degradation mechanisms in hematological malignancies.
Product Specifications
CAS Number
2929304-61-8
Product Name Alternative
HistoneMethyltransferase, Histone Methyltransferase, NSD
Field of Research
Epigenetics & Chromatin, Immunology & Inflammation
Purity
96.44% (May vary between batches)
Solubility
PBS pH 7.2:5 mg/mL (7.17 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (2.87 mM) ; Ethanol:30 mg/mL (43 mM) ; DMSO:30 mg/mL (43 mM) ; H2O:5 mg/mL (7.17 mM) ; DMF:30 mg/mL (43 mM)
Smiles
O=C (O) C (F) (F) F.O=C (NC1=CC=C (C=C1) C (=O) NCCCCCCN) C2=CC=C (C=C2) CN (C (=O) C3=CC=C4NC (=O) COC4=C3) C5CC5
Molecular Formula
C35H38F3N5O7
Molecular Weight
697.7
Storage Conditions
-20°C
Notes
For research use only.
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