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UNC8153 TFA

UNC8153 TFA is a potent and selective degrader of the NSD2 protein, demonstrating anti-proliferative activity in MM.1S multiple myeloma cells. This compound serves as a valuable chemical probe for oncology research, particularly in studying epigenetic targets and protein degradation mechanisms in hematological malignancies.

Product Specifications

CAS Number

2929304-61-8

Product Name Alternative

HistoneMethyltransferase, Histone Methyltransferase, NSD

Field of Research

Epigenetics & Chromatin, Immunology & Inflammation

Purity

96.44% (May vary between batches)

Solubility

PBS pH 7.2:5 mg/mL (7.17 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (2.87 mM) ; Ethanol:30 mg/mL (43 mM) ; DMSO:30 mg/mL (43 mM) ; H2O:5 mg/mL (7.17 mM) ; DMF:30 mg/mL (43 mM)

Smiles

O=C (O) C (F) (F) F.O=C (NC1=CC=C (C=C1) C (=O) NCCCCCCN) C2=CC=C (C=C2) CN (C (=O) C3=CC=C4NC (=O) COC4=C3) C5CC5

Molecular Formula

C35H38F3N5O7

Molecular Weight

697.7

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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