(S) -5-hydroxy-6-methoxy Duloxetine maleate
(S) -5-Hydroxy-6-methoxy Duloxetine is an active (S) -duloxetine metabolite formed via CYP1A2/CYP2D6. It acts as a triple monoamine reuptake inhibitor, blocking human SERT, NET, and DAT with Kis of 266, 920, and 2,814 nM, respectively. This compound is a valuable research tool for in vitro neuropharmacology studies of transporter inhibition.
Product Specifications
Field of Research
Pharmacology & Drug Discovery
Smiles
OC (/C=C\C (O) =O) =O.CNCC[C@@H] (C1=CC=CS1) OC2=CC=CC3=C (O) C (OC) =CC=C32
Molecular Formula
C19H21NO3S.C4H4O4
Molecular Weight
459.51
Storage Conditions
-20°C
Notes
For research use only.
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