C-02
C-02 is a PROTAC molecule that degrades hexokinase 2, demonstrating cytotoxic effects in various cancer cell lines and suppressing glycolysis in vitro. In vivo, it reduces tumor growth and induces pyroptosis in a 4T1 mouse model, supporting its study in oncology and cancer metabolism research.
Product Specifications
Smiles
O=C (N (C1C (NC (CC1) =O) =O) C2=O) C3=C2C=CC=C3NCCCCNC (C4=NN (CC5=C (Cl) C=C (Cl) C=C5) C6=C4C=CC=C6) =O
Molecular Formula
C32H28Cl2N6O5
Molecular Weight
647.51
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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