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Sulfonadyn-47

Sulfonadyn-47 is a dynamin GTPase inhibitor with an IC50 of 3.5 μM, disrupting clathrin-mediated endocytosis in cells and synaptic vesicle recycling in synaptosomes. It demonstrates in vivo anticonvulsant efficacy in a 6 Hz corneal kindling mouse seizure model at 30-60 mg/kg, supporting research in neurobiology and endocytosis.

Product Specifications

Smiles

BrC1=CC=C (/C=C/CNCCCNS (=O) (C2=C (C=CC=C3) C3=CC=C2) =O) C=C1

Molecular Formula

C22H23BrN2O2S

Molecular Weight

459.40

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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