BDW568

BDW568 is a STING agonist prodrug that activates the STING pathway, as demonstrated by its induction of STING transcriptional activity (EC50 = 7.6 μM) and phosphorylation of TBK1 and IRF3 in THP-1 cells. This compound is a valuable research tool for studying innate immune signaling in cancer immunotherapy and inflammatory disease models, both in vitro and in vivo.