BDW568
BDW568 is a STING agonist prodrug that activates the STING pathway, as demonstrated by its induction of STING transcriptional activity (EC50 = 7.6 μM) and phosphorylation of TBK1 and IRF3 in THP-1 cells. This compound is a valuable research tool for studying innate immune signaling in cancer immunotherapy and inflammatory disease models, both in vitro and in vivo.
Product Specifications
CAS Number
335401-44-0
Field of Research
Immunology & Inflammation
Smiles
O=C (OC) CSC1=NN=C2N1C=NC3=C2C (C) =C (C) S3
Molecular Formula
C12H12N4O2S2
Molecular Weight
308.38
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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